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IQ Gain vs. Cost of IVF + PGT-P

Expected first-child IQ gain from embryo selection at each additional IVF cycle, accounting for transfer loss. Herasight PGT-P, European parents, mother age 30.

Assumptions: Elective baseline profile · Mother age 30 · Both parents European · Herasight PGT-P (r² = 0.225 for IQ) with lab handling biopsies · CNY Fertility ($8.1k/cycle + $54k one-time) vs. Avg. Boston clinic ($23.9k/cycle + $55k one-time) · 67% implantation rate per transfer · IVF pipeline: SART-calibrated ZINB egg retrieval → maturity → fertilization → blastocyst → euploidy → warming · IQ gain computed from expected order statistics of within-family PGS distribution, weighted across the full embryo count distribution